Database Record

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SAGD:  Sex-Associated Gene Database

info ID: NBDC02571
info Database name: SAGD
info Alternative name: Sex-Associated Gene Database
info URL: 
info Database maintenance site: College of Life Science and Technology, Huazhong Agricultural University
info Country/Region: China
info Database description: Many animal species present sex differences. Sex-associated genes (SAGs), which have female-biased or male-biased expression, have major influences on the remarkable sex differences in important traits such as growth, reproduction, disease resistance and behaviors. However, the SAGs resulting in the vast majority of phenotypic sex differences are still unknown. To provide a useful resource for the functional study of SAGs, we manually curated public RNA-seq datasets with paired female and male biological replicates from the same condition and systematically re-analyzed the datasets using standardized methods. We identified 27,793 female-biased SAGs and 64,043 male-biased SAGs from 2,828 samples of 21 species, including human, chimpanzee, macaque, mouse, rat, cow, horse, chicken, zebrafish, seven fly species and five worm species. All these data were cataloged into SAGD, a user-friendly database of SAGs where users can browse SAGs by gene, species, drug, and dataset. In SAGD, the expression, annotation, targeting drugs, homologs, ontology and related RNA-seq datasets of SAGs are provided to help researchers to explore their functions and potential applications in agriculture and human health.
info Organism(s) covered: Bos taurus (), Caenorhabditis (), Danio rerio (), Drosophila (), Equus caballus (), Gallus gallus (), Homo sapiens (), Macaca mulatta (), Mus musculus (), Pan troglodytes (), Pristionchus pacificus (), Rattus norvegicus ()
info Tag - Target: Genome/Gene
info Tag - Information type: Expression, Localization
info Reference(s) - PubMed ID/DOI: 
PubMed ID:
30380119
DOI:
10.1093/nar/gky1040
info Language(s): English
info Operational status: Active
info Link(s) to Downloadable data: http://bioinfo.life.hust.edu.cn/SAGD#!/download
info Link(s) to Metadata of downloadable data: -
info Link(s) to Terms of use: -
info Link(s) to "How to use": http://bioinfo.life.hust.edu.cn/SAGD#!/help
info Contact information of database: http://bioinfo.life.hust.edu.cn/SAGD#!/contact/
info Link(s) to API / SPARQL endpoint -