SIGNOR, the SIGnaling Network Open Resource: SIGNOR
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| Database maintenance site: | Bioinformatics and Computational biology Unit, Molecular genetics Lab, University of Rome Tor Vergata |
| Country/Region: | Italy |
| Database description: | SIGNOR, the SIGnaling Network Open Resource, organizes and stores in a structured format signaling information published in the scientific literature. The captured information is stored as binary causative relationships between biological entities and can be represented graphically as activity flow. The entire network can be freely downloaded and used to support logic modeling or to interpret high content datasets. The core of this project is a collection of more than 11000 manually-annotated causal relationships between proteins that participate in signal transduction. Each relationship is linked to the literature reporting the experimental evidence. In addition each node is annotated with the chemical inhibitors that modulate its activity. The signaling information is mapped to the human proteome even if the experimental evidence is based on experiments on mammalian model organisms. |
| Organism(s) covered: | , , |
| Tag - Target: | Protein |
| Tag - Information type: | Bibliography/Documents, Interaction/Pathway |
| Reference(s) - PubMed ID/DOI: | PubMed ID: DOI: |
| Language(s): | English |
| Operational status: | Active |
| Link(s) to Downloadable data: | - |
| Link(s) to Metadata of downloadable data: | - |
| Link(s) to Terms of use: | - |
| Link(s) to "How to use": | - |
| Contact information of database: | - |
| Link(s) to API / SPARQL endpoint | - |
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Link to LSDB Archive:
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Link to MEDALS Database list:
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Link to TogoTV:
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Link to FAIRsharing:
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https://fairsharing.org/10.25504/FAIRsharing.ss78t4 |
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Similar databases:
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PINT Death Domain Database VirHostNet 2.0 HINT Interaction Reference Index Web Interface VirusMentha The Signaling Gateway PCDq Molecular INTeraction database ProLINT |
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Record maintainer
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See the corresponding part in the FAIRsharing record. |
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Record source:
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 (2018-12-21)
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Date of creation of this record:
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2019-03-28 |
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Last update date of this record:
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2020-07-09 |
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Record license:
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Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license |