Target Central Resource Database: TCRD
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| Database maintenance site: | European Commission FP7, Icahn School of Medicine at Mount Sinai, UNM School of Medicine, University of Miami School of Medicine |
| Country/Region: | United States |
| Database description: | TCRD is the central resource behind the Illuminating the Druggable Genome Knowledge Management Center (IDG-KMC). TCRD contains information about human targets, with special emphasis on four families of targets that are central to the NIH IDG initiative: GPCRs, kinases, ion channels and nuclear receptors. Olfactory GPCRs (oGPCRs) are treated as a separate family. A key aim of the KMC is to classify the development/druggability level of targets. The official public portal for TCRD is Pharos (pharos.nih.gov). Based on modern web design principles the Pharos interface provides facile access to all data types collected by the KMC. Given the complexity of the data surrounding any target, efficient and intuitive visualization has been a high priority, to enable users to quickly navigate & summarize search results and rapidly identify patterns. A critical feature of the interface is the ability to perform flexible search and subsequent drill down of search results. Underlying the interface is a RESTful API that provides programmatic access to all KMC data, allowing for easy consumption in user applications. |
| Organism(s) covered: | |
| Tag - Target: | Drug, Protein |
| Tag - Information type: | Interaction/Pathway |
| Reference(s) - PubMed ID/DOI: | PubMed ID: DOI: |
| Language(s): | English |
| Operational status: | Active |
| Link(s) to Downloadable data: | - |
| Link(s) to Metadata of downloadable data: | - |
| Link(s) to Terms of use: | - |
| Link(s) to "How to use": | - |
| Contact information of database: | - |
| Link(s) to API / SPARQL endpoint | - |
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Link to LSDB Archive:
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Link to MEDALS Database list:
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Link to TogoTV:
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Link to FAIRsharing:
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https://fairsharing.org/10.25504/FAIRsharing.1gn47b |
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Similar databases:
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Therapeutically Relevant Multiple Pathways Database GLIDA Drug Adverse Reaction Target BindingDB database of measured binding affinities phosprof TTD, Therapeutic Target Database PINT Trypanosomes Database Xenobiotics Metabolism Database DGiDB |
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Record maintainer
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See the corresponding part in the FAIRsharing record. |
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Record source:
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 (2018-12-21)
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Date of creation of this record:
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2019-03-28 |
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Last update date of this record:
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2019-03-28 |
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Record license:
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Creative Commons Attribution and Share-alike (CC-BY-SA) International 4.0 license |